I think it's going to be a router issue. It may handle IPv6 on the CPU instead of a dedicated network chip (keyword is "hardware offloading"), and that could result in high load when handling too many IPv6 connections at once. Ask the manufacturer about it.
no other program has caused this to happen either.
Instead of turning off IPv6 entirely, set the Network mode to "IPv4 Preferred" and see if it has an sensible effect.
Also test Tixati's portable version with DHT, but no active torrents and see if it has an sensible effect.