I'm a pretty big fan of Tixati as a client and recently suggested a friend of mine (who happens to be blind) try it. They did, but according to them, it was lacking some accessibility features for screenreaders such as JAWS. The primary issue seems to be that the buttons aren't labeled, so screenreaders read every button as "button" instead of the text of the button itself. From what I've heard, adding such labels isn't too difficult, although I don't have any personal expertise in the field to say otherwise, but in the interest of making Tixati accessible to the blind community, I think it could definitely be a valuable addition.